EPIDEMIOLOGICAL CLINICAL CHARACTERISTICS OF SEVERE ACUTE RESPIRATORY INFECTION WITH RESPIRATORY SYNCYTIAL VIRUS INFECTION IN THE INTENSIVE CARE UNIT OF THE NATIONAL HOSPITAL OF PEDIATRICS
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Abstract
Objectives: Describe the epidemiological, clinical and laboratory characteristics of the patient severe acute respiratory infection with respiratory syncytial virus infection in the intensive care unit of the National Hospital of Pediatrics. Subjects and methods: This prospective descriptive study included 83 patients diagnosed with severe acute respiratory infection with respiratory syncytial
virus infection in the intensive care unit of the National Hospital of Pediatrics from 5/2020 to 5/2021. Result: The medium age is 3.3 ± 2.1 months, the male and female ratio is 2:1. Most of the cases are admitted to hospital in the autumn - winter season (from October to December). Patients with severe acute respiratory infections accounted for 72.3%. Very severe acute respiratory infections accounted for 27.7%. Severe life dysfunction: grade 3 respiratory failure accounted for 100%, circulatory failure accounted for 31.3%, and multi-organ failure 34.9%. The PRISM and PELOD scores are relatively high.
Most of the patients had comorbid infections with SIRS 68.7%, increased CRP and procalcitonin 47% and 78.3%. Premature birth 30,1%, birth defects 40,9%, underlying disease 30,1%, Co-infection 53%. Bacterial co-infection is a factor related to the severity of acute respiratory infections with RSV infection (p<0,05).
Conclusion: Severe clinical manifestations but unspecific signs.High rates of premature birth, birth defects, underlying diseases and co-infection.Bacterial co-infection is a factor related to the severity of acute respiratory infections with RSV infection.
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Keywords
Nhiễm khuẩn hô hấp cấp nặng, virus hợp bào hô hấp.
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