THE CLINICAL FEATURES AND BACTERIAL ETIOLOGIES THAT CAUSE COMMUNITYACQUIRED PNEUMONIA IN CHILDREN AT 108 MILITARY CENTRAL HOSPITAL
##plugins.themes.vojs.article.main##
Abstract
Objectives: Describe the clinical features and bacterial etiologies that cause communityacquired pneumonia in children.
Study subjects and methods: A cross-sectional descriptive study of 207 children with community-acquired pneumonia hospitalized from April 1, 2023 to March 31, 2024.
Results: The male ratio was 54.1%; the age group from 2 months to 5 years old accounted for 59.4%. The main clinical features were cough 100%; fever 56.03%, tachypnea 37.68%; coarse rales: 67.63%, respiratory failure 10.14%. The white blood cell count was 14.65±4.43 G/l; CRP levels increased to 22.49±28.71 mg/l. On chest X-ray, localized lesions accounted for the majority at 48.6%. There were 77.3% positive samples in real-time PCR tests of nasopharyngeal specimens; among them, those positive for one bacterium accounted for the highest at 60.78%; both coinfections of two or three bacterial were found. The positivity rate for each agent H.inuenzae, S.pneumoniae, and M.pneumoniae gradually decreased by 48.36%; 47.05%; 41.83 %. The percentages of samples positive for bacteria in nasopharyngeal uid culture was 74.7%; among them, the positive samples for S.pneumoniae accounted for the highest rate of 28.34%.
Conclusion: Common clinical features in pediatric community-acquired pneumonia are cough, fever, tachypnea, coarse rales, and respiratory failure. The major pathogens are H.infuenzae, S.pneumoniae, and M.pneumoniae
##plugins.themes.vojs.article.details##
Keywords
community acquired pneumonia, children, real-time PCR, bacterial culture
References
2. Đoàn Thị Mai Thanh, Ngô Anh Vinh. Căn nguyên vi khuẩn và một số yếu tố liên quan gây viêm phổi cộng đồng ở trẻ em tại Bệnh viện Nhi trung ương bằng kỹ thuật Real time pcr đa mồi. Tạp chí Y học Việt Nam 2023;532(2):252-257. https://doi. org/10.51298/vmj.v532i1.7316
3. McAllister DA, Liu L, Shi T et al. Global, regional, and national estimates of pneumonia morbidity and mortality in children younger than 5 years between 2000 and 2015: a systematic analysis. Lancet Glob Health 2019;7(1):e47-e57. https://doi.org/10.1016/s2214-109x(18)30408-x
4. Nguyễn Thị Hà, Đoàn Mai Thanh và Nguyễn Thị Yến. Đặc điểm lâm sàng và căn nguyên gây viêm phổi cộng đồng trẻ em tại khoa quốc tế Bệnh viện Nhi trung ương. Tạp chí nghiên cứu y học 2020;131(7):67-73.
5. Phạm Văn Đếm, Nguyễn Thành Nam. Đặc điểm lâm sàng, cận lâm sàng và căn nguyên vi khuẩn trên trẻ mắc viêm phổi tại Khoa Nhi, Bệnh viện Bạch Mai. Tạp chí khoa học Đại học Quốc gia Hà Nội: Khoa học Y Dược 2020;36(2):55-63. https://doi.org/10.25073/2588-1132/vnumps.4236
6. Phạm Văn Hưng, Ngô Thị Minh, Nguyễn Thị Hương. Đặc điểm lâm sàng, cận lâm sàng và kế quả điều trị viêm phổi tập trung ở trẻ em tại Bệnh viện Nhi Hải Dương năm 2023. Tạp chí y học Việt Nam 2024;535(1B):333-337.https://doi.org/10.51298/vmj.v535i1B.8457
7. Phuong TKN, Hoang TT, Dominic A et al. Characterisation of children hospitalised with pneumonia in central Vietnam: a prospective study. European Respiratory Journal 2019;54(1):1802256. https://doi.org/10.1183/13993003.02256-2018
8. Katz SE, Williams DJ. Pediatric CommunityAcquired Pneumoniae in the United States Changing Epidemiology, Diagnostic and Therapeutic Challenges, and Areas for Future Research. Infect Dis Clin North Am 2018;32(1):47-63. https://doi.org/10.1016/j.idc.2017.11.002
9. Chochua S, D’Acremont V, Hanke C et al, Increased Nasopharyngeal Density and concurrent Carriage of streptococcus pneumoniae, Haepmophilus Inuenzae, and Moraxella catarrhalis are Associated with Pneumoniae in Febrile Children. PLoS One 2016;11(12):1-12. https://doi.org/10.1371/journal.pone.0167725
10. WHO. Levels and trends in child mortality. WHO; (2015). http://www.who. int/maternal_child_adolescent/documents/levels_trends_child_morta lity_2015/en/. Accessed 14 Aug 2020.
11. Shekhawat Y, Sharma P, Singh A et al. Bacreriological and clinical prole of community acquired pneumoniae in hospitalized children with associated comorbidity in a tertiary care centre of western Rajasthan, India. Journal of Contemporary Pediatrics Shekhawa 2016;3(4):1380-1384.http://dx.doi.org/10.18203/2349-3291.ijcp20163682