ĐẶC ĐIỂM U THẬN TRẺ EM TẠI BỆNH VIỆN NHI TRUNG ƯƠNG (2017-2022)
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Abstract
- Malignant kidney tumors in children account for about 5.2% of annual cancers in children under 15 years old, of which nephroblastoma (Wilms Tumor) is the most common cancer (~90% in Europe) and have the ability to respond to effective treatment. In Vietnam, research on pediatric kidney tumors and nephroblastoma is currently limited. Objectives: Survey on the incidence of kidney tumors in children at the National Children's Hospital (2017-2022) and some related factors. Materials and methods: 181 children under 15 years old were histopathologically diagnosed with kidney tumors at the National Children's Hospital (2017-2022). Results: Among 181 children with kidney tumors (99 boys and 82 girls), Wilms tumor had the highest incidence (69.1%), average age 28.4 months, mainly in children under 5 years old (92%). ). Non-Wilms' tumors include clear cell sarcoma of the kidney (8.3%), malignant rhabdoid tumor of the kidney (6.6%), renal cell carcinoma (6.6%), congenital mesoblastic nephroma (6.1%) and other rare kidney tumors. Conclusion: Wilms tumor is the most common kidney tumor in children, although non-Wilms tumors are not rare.
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Keywords
Renal tumor, children, nephroblastoma
References
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3. Libes J, Hol J, Neto JC de A et al. Pediatric renal tumor epidemiology: Global perspectives, progress, and challenges. Pediatr Blood Cancer 2023;70(1):e30006. https://doi.org/10.1002/pbc.30343
4. Vu MT, Shalkow J, Naik-Mathuria B et al. Wilms’ tumor in low- and middle-income countries: survey of current practices, challenges, and priorities. Ann Pediatr Surg 2022;18(1):28. http://dx.doi.org/10.1186/s43159-022-00163-6
5. Ooms AHAG, Vujanić GM, D’Hooghe E et al. Renal Tumors of Childhood—A Histopathologic Pattern-Based Diagnostic Approach. Cancers 2020;12(3):729. https://doi.org/10.3390/cancers12030729
6. Vujanić GM, Gessler M, Ooms AHAG et al. The UMBRELLA SIOP–RTSG 2016 Wilms tumour pathology and molecular biology protocol. Nat Rev Urol 2018;15(11):693-701. https://doi.org/10.1038/s41585-018-0100-3
7. Bozlu G, Cıtak EC. Evaluation of renal tumors in children. Türk J Urol 2018;44(3):268-273. https://doi.org/10.5152/tud.2018.70120
8. Lee JS, Sanchez TR, Wootton-Gorges S. Malignant renal tumors in children. J Kidney Cancer VHL 2015;2(3):84-89. https://doi.org/10.15586/jkcvhl.2015.29
9. Nakata K, Ito Y, Magadi W et al. Childhood cancer incidence and survival in Japan and England: A population‐based study (1993‐2010). Cancer Sci 2018;109(2):422-434. https://doi.org/10.1111/cas.13457