MILD ENCEPHALOPATHY WITH A REVERSIBLE SPLENIAL LESION ASSOCIDATE WITH GASTROINTESTINAL VIRAL INFECTION: A REPORT OF 3 CASES AT VINMEC TIMES CITY INTERNATIONAL GENERAL HOSPITAL
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Abstract
Mild encephalopathy with a reversible splenial lesion (MERS) is a rare neurological disease characterised by clinical symptoms of mild encephalitis accompanied with specific corpus callosum lesions on cranial MRI - usually completely reversible without sequelae [1]. The disease is caused by various etiologies, but the most common causes are gastrointestinal viruses such as Rotavirus, Norovirus, Adenovirus…. Other viruses including influenza virus, mumps virus, dengue virus, and bacteria such as Mycoplasma, pneumococcus, streptococcus, Escherichia coli, and Klebsiella have been reported as causative agents of MERS [2] [3]. Etiologies related to anticonvulsant drugs and Kawasaki disease have also been described [4]. We report three cases of mild encephalopathy with reversible corpus callosum lesions associated with gastrointestinal viruses treated at Vinmec Times City International General Hospital during a two-year period (2024-2025) in order to share our experiences in diagnosing and treating this rare disease.
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Keywords
gastrointestinal viral, Mild Encephalopathy with a Reversible Splenial lesion - MERS, children
References
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