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Published: 2026-06-24
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DOI: https://doi.org/10.52724/tcnk.v19i2.496
Issue
Vol. 19 No. 2 (2026)
Section
Research

CLINICAL EPIDEMIOLOGICAL CHARACTERISTICS AND CAUSES OF FEBRILE NEUTROPENIA AT HAI PHONG CHILDREN’S HOSPITAL

Sang Nguyen Ngoc1, Hoa Tran Thi Ngoc2, Thao Vu Thi Nhu2, Hoa Bui Tu1
1 Hai Phong University of Medicine and Pharmacy
2 Hai Phong Children’s Hospital

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Abstract

Objective: To describe the clinical epidemiological characteristics and etiologies of febrile neutropenia in children.


Subjects: A total of 1,104 pediatric patients with febrile neutropenia treated at Hai Phong Children’s Hospital from September 1, 2023 to August 31, 2025.


Methods: An analytical cross-sectional study was conducted.


Results: The mean age was 5.18 years, with a male-to-female ratio of 2.2:1; 57.43% of patients lived in urban areas. The mean body temperature on admission was 39.17 ± 0.65°C. The most common clinical manifestations were respiratory infections (48.82%), gastrointestinal infections (28.08%), and skin infections (22.37%). Viral etiologies predominated, with 752 cases identified, among which Dengue virus was the most common (67.69%), followed by Influenza A (11.44%) and measles (7.85%). Bacterial pathogens were isolated in 43 cases, most commonly Haemophilus influenzae (58.14%).


Conclusion: Febrile neutropenia was commonly observed in children over 1 year of age, predominantly presenting with upper respiratory tract infections. Viral infections were the leading cause, followed by a smaller proportion of bacterial pathogens.

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Keywords

children, fever, neutropenia

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