DỊ ỨNG THỨC ĂN QUA TRUNG GIAN IGE TẠI BỆNH VIỆN NHI ĐỒNG 1: VAI TRÒ CỦA NGHIỆM PHÁP THỬ THÁCH ĐƯỜNG MIỆNG
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Abstract
Objectives: IgE-mediated food allergy is an increasingly recognized issue in pediatrics. The oral food challenge (OFC) is the gold standard for confirming diagnosis and assessing tolerance.
Subjects and methods: A retrospective study was conducted on 26 children suspected of or diagnosed with food allergy at Children’s Hospital 1 from January 2016 to January 2024.
Results: The study showed that the median age was 10.5 months, and 84.6% of the children were ≤24 months.. Common foods involved were cow’s milk, eggs, and shrimp. The OFC positivity rate was 19.2% (16.7% in the diagnostic group and 21.4% in the tolerance assessment group). All children with a positive OFC presented with urticaria; one also had rhinorrhea; no cases of anaphylaxis were recorded. Only one child required oral antihistamines. Children with negative OFC results tolerated the food well and resumed a normal diet.
Conclusions: OFC is a crucial tool for confirming diagnosis, evaluating tolerance, and preventing unnecessary dietary restrictions.
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Keywords
IgE-mediated food allergy, oral food challenge, children, food allergy diagnosis, food tolerance
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