EVALUATION OF TREATMENT OUTCOMES IN PATIENS WITH DENGUE HEMORRHAGIC FEVER REQUIRING INTRAVENOUS FLUID THERAPY AT DANANG HOSPITAL FOR WOMEN AND CHILDREN
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Abstract
Objective: To describe the clinical and subclinical characteristics and evaluate treatment outcomes in pediatric patients with dengue hemorrhagic fever (DHF) requiring intravenous fuid therapy at Danang Hospital for Women and Children.
Methods: A cross-sectional descriptive study was conducted on 53 children aged 1 month to under 16 years, hospitalized at the Department of Tropical Medicine and Pediatric ICU from October 2023 to September 2024. Patients were diagnosed with DHF and received intravenous fuid therapy per national guidelines. Clinical, laboratory, and treatment data were collected and analyzed using SPSS 22.0.
Results: Children with normal nutritional status accounted for 60.4%, while those who were overweight or obese accounted for 32,1%. Most patients were hospitalized on the 4th (34%) and 5th (41.5%) day of illness. The duration of fever typically ranged from 4 to 5 days (77.4%). Severe DHF was observed in 60.4% of cases, and DHF with warning signs in 39.6%. Among those with severe DHF, the rates of shock and respiratory failure were 49.1% and 39.6%, respectively. The mean volume of intravenous fuids administered in the severe DHF group was 98.3 ± 66.9 ml/kg, compared to 60.3 ± 30 ml/kg in the warning sign group (p<0.05). The average duration of fuid therapy for all DHF patients was 25.5 ± 10 hours, with 21.7 ± 10.1 hours in the warning sign group and 28 ± 9.2 hours in the severe DHF group (p< 0.05).
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Keywords
dengue hemorrhagic fever, severe, warning sign, fuid therapy
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