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Published: 2025-08-22
Abstract Views: 8
Issue
Vol. 18 No. 1 (2025)
Section
Research

HEALTH – RELATED QUALITY OF LIFE IN CHILDREN WITH CRANIOPHARYNGIOMA TREATED AT THE NATIONAL CHILDREN’S HOSPITAL

Phuong Hong Le1, Vu Hung Cao2, Trung Kien Pham1
1 University of Medicine and Pharmacy, Vietnam National University, Hanoi
2 Vietnam National Children’s Hospital

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Abstract

Objectives: To evaluate health-related quality of life (HRQoL) in children with craniopharyngioma treated at the National Children’s Hospital.


Methods: A cross-sectional descriptive study was conducted using the PedsQL™ 1.0 (quality of life assessment for pediatric brain tumor patients) and PedsQL™ 4.0 (quality of life assessment for children with chronic diseases) tools. The study included 35 patients diagnosed with craniopharyngioma and treated at the Neurology Center of the National Children’s Hospital from January 2020 to November 2024.


Results: The average age was 9.4 ± 3.8 years, and the mean age at diagnosis was 7.3 ± 3.8 years. Adamantinomatous craniopharyngioma accounted for 88.6% of cases. Surgery was the primary treatment (100%), with 82.9% undergoing surgery alone. All patients required hormone replacement therapy post-treatment.Quality of life assessments showed no signifcant diferences between child- and parent-reported scores (PedsQL™ 1.0, PedsQL™ 4.0). Children aged 8–12 had higher quality of life scores (57.51 ± 21.28) than other groups. The learning domain scores were low across all groups, indicating signifcant academic challenges for children with chronic illness.Older children had better cognitive (78.6 ± 5.1) and motor function (98.1 ± 4.8). Factors afecting quality of life included early diagnosis, socioeconomic status, treatment access, age, and academic performance..


Conclusion: The overall quality of life of children with craniopharyngioma treated at the National Children’s Hospital was moderate.

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Keywords

Craniopharyngioma, quality of life, craniopharyngioma treatment

References

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