MỐI LIÊN QUAN GIỮA THỂ TÍCH TRUNG BÌNH HỒNG CẦU (MCV) VÀ MÔ HÌNH BỆNH TẬT TRẺ EM TẠI BỆNH VIỆN PHÚ VANG - THỪA THIÊN-HUẾ THE RELATIONSHIP BETWEEN MEAN CORPUSCULAR VOLUME (MCV) AND DISEASE PATTERNS IN INPATIENT CHILDREN AT PHU VANG HOSPITAL - THUA THIEN-HUE
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Abstract
Introduction: Recent research has explored the prognostic value of Mean Corpuscular Volume (MCV) in various adult clinical scenarios. We hypothesized that a similar association might exist in children and sought to investigate this.
Objective: To examine the relationship between MCV and prevalent pediatric diseases, and to identify a low MCV threshold that signifcantly elevates disease risk.
Subjects and Methods: A cross-sectional, retrospective study was conducted on the medical records of 2,160 pediatric inpatients at the Pediatrics Department of Phu Vang Hospital between January and June 2024.
Results: Across all age groups, a low MCV < 80 was associated with a 1.4-fold increase in the risk of respiratory diseases, with similar fndings for MCV < 79. Particularly for pneumonia, low MCV levels below 80 was linked to a 1.6 to 1.8-fold increase in pneumonia risk across all age group. Furthermore, an MCV < 76 was linked to a 1.8-fold increase in pneumonia risk, while an MCV < 80 was associated with a 2.1-fold increase in children aged 6-24 months.
Conclusion: Our study confrmed a signifcant association between low MCV and pediatric morbidity, clearly distinguishing low MCV from anemia. This research highlights a novel approach to the interpretation of the MCV index by identifying an MCV < 80 as risk factor for pediatric respiratory diseases, particularly pneumonia in children aged 6-24 months, and MCV<76 as risk factor for pediatrics pneumonia.
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Keywords
Pediatrics disease patterns, Morbidity, Respiratory diseases, Pneumonia, Microcytosis, MCV<76, MCV<80
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