Bui Ngoc Lan1, Le Thi Kim Ngoc1, Hoang Ngoc Thach1, Phan Canh Duy2
1 , Vietnam National Children’s Hospital, Hanoi, Vietnam
2 , Hue Central Hospital, Vietnam


Tóm tắt

Pleuropulmonary blastoma (PPB) is a rare malignant tumor in childhood cancer. This type of tumor is diffi cult to identify and can easily be misdiagnosed. The International PPB protocol is a complicated and aggressive protocol. It is not easily applicable to developing countries where hospitals do not have enough resources. We are presenting the fi rst case successfully treated in Vietnam, using limited medical resources. The patient (22 month old, male) was diagnosed with
congenital cystic adenomatoid malformation in his 1st hospital admission. After 6 months of
onset, the patient was diagnosed with PPB type II in 4th hospitalization following analysis of a
lung CT scan and a pathology report. After the aggressive chemotherapy regimen, patient had
two episode of severe neutropenia and infection but luckily recovered. The patient received chemotherapy and surgery treatment at our hospital, but received radiation under general anesthesia and rehabilitation therapy to improve respiration at another hospital over 600 km away. It has been 1.5 years after entering remission, and he is starting kindergarten. Conclusion: Lungs CT scan and pathology should been analyzed carefully to avert misdiagnosis PPB in patients with cyst or mixed cyst and solid part in lunto the free central pathology review. Two factors important to the successful application of the
protocol are good supportive care and the multidisciplinary collaboration between medical facilities to provide proper resources during treatment. We hope to recreate more successful outcomes not only in Vietnam but also in all developing All cases of suspected PPB send 


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