CLINICAL AND PARACLINICAL FEATURES OF CORONARY ARTERY ANEURYSMS IN KAWASAKI DISEASE
Objectives: To describe clinical and subclinical features according to level of coronary artery
aneurysm (CAA) in Kawasaki disease. Patients and methods: 545 patiens with Kawasaki disease at Cardiovascular Center - Vietnam National Children’s Hospital between January 2019 and June 2022. Results: Patients were classifi ed as 4 groups: no involvement, small aneurysm, medium aneurysm, large or giant aneurysm (GAA). The rates of 4 groups were: 44.6%, 19.4%, 18.2%, 7%. The average age at diagnosis of 12.6 months, 49.4% under 12 months, the ratio of male: female approximates 1.5:1, 11.7% had atypical Kawasaki disease with lowest in no involvement group and highets in GAA group. Day at diagnosis, day of IVIG, total fever duration, IVIG-nonresponsive, the leucocyte
count pre-IVIG, CRP pre-IVIG, platelets post-IVIG increased gradually with levels of CAA, but hemoglobin pre-IVIG, albumin decreased with
levels of CAA, statistically signifi cant diff erences between four groups (p<0.05). Conclusion: In the subacute phage, there is
a high rate of CAA. It had higher duration of diagnosis, Resistance to IVIG , leucocyte count, CRP and lower albumin, hemoglobin, age with another groups. The infl ammatory response status increases with the level of CAA. There are statistically signifi cant diff erences in some clinical and labotory variables in four groups.
Kawasaki disease, level of coronary artery aneurysm
Tài liệu tham khảo
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