CHARACTERISTIC FINDINGS OF CORONARY ARTERY LESIONS IN INTRAVENOUS IMMUNOGLOBULIN NON-RESPONSIVE KAWASAKI DISEASE
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Tóm tắt
Objectives: To determine characteristic findings of coronary artery lesions in acute phase
of the intravenous immunoglobulin (IVIG) -non-responsive and -responsive Kawasaki children
in the Vietnam National Children’s Hospital (VNCH). Methods: Prospective, descriptive study
on 251 patients who were diagnosed with Kawasaki disease at Vietnam National Children’s
Hospital from January 2019 to June 2020. Results: 13.9% of patients was non-responsive with
IVIG; 35.1% of patients had coronary artery lesions (CAL). Severity of CAL was mainly mild and
moderate. 60% of IVIG-non-responsive patients had CAL with 28.6% mild, 28.6% moderate and
42.8% severe cases. IVIG-non-responsive patients had higher rate and more severe level of CAL
than IVIG-responsive patients. White blood cells count, neutrophil count and serum C-reactive
protein(CRP), albumin had statistically significant differences between two groups (p<0,05).
Conclusions: IVIG-non-responsive patients had higher rate and more severe level of CAL than
IVIG responsive patients. There were statistically significant differences in some laboratory
variables between IVIG- non-responsive and -responsive group.
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Từ khóa
Kawasaki disease, intravenous immunoglobulin resistant Kawasaki.
Tài liệu tham khảo
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