Chloride intake and metabolic acidosis in preterm infants at The National Hospital of Pediatrics

Nguyen Thi Quynh Nga

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Tóm tắt

Background: Optimal chlorine intake in premature infants has been very little studied, while high chlorine intake has been shown to be associated with hyperchloremic metabolic acidosis. Objective: To describe the first 10 days after birth chlorine intake in premature infants less than 32 weeks and to investigate the association between high chlorine intake and metabolic acidosis. Subjects and methods: Prospective Descriptive Study on 95 premature infants under 32 weeks admitted to hospital <24 hours of age and treated for at least 10 days after birth, at the Vietnam National Children’s Hospital from July 2018 to June / 2019. Results: Total accumulated chlorine intake reached 49.95 ± 11.07 mmol / kg in the first 10 days. The amounts of chlorine intake in unintentional fluids and in intravenous nourishing fluids are the two main sources of chlorine in the first 10 days after birth. There was a correlation between high chlorine intake in the first 10 days (> 47 mmol / kg) and metabolic acidosis. Conclusion: High chlorine intake > 47 mmol / kg in the first 10 days after birth is associated with metabolic acidosis in premature infants less than 32 weeks. Chlorine intake, premature infants, metabolic acidosis.

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